雖然人體會自然地面臨「老化」且無法避免，但「老化」的速度卻可以控制！根據研究指出，人體血液中的穀胱甘肽（GSH）能避免DNA氧化、清除自由基，因此又被稱為「抗氧化之母」。
穀胱甘肽在體內的含量多寡，也被實驗證實是健康的關鍵，若要抗老化，首要條件就是提升血液中的穀胱甘肽濃度，從體內真正提升抗氧化能力，才能由內而外抵禦對抗老化！
多項研究證實：穀胱甘肽有效美白！抑製黑色素，重現淨白透亮肌
2019年一份研究文獻綜合多項研究（研究連結）結果顯示，穀胱甘肽具有抑制皮膚黑色素生成的能力，能夠使肌膚呈現亮白效果，同時改善皺紋、增強彈性並減輕斑點。此外，國際皮膚學會的研究結果（研究連結）也證實，在服用穀胱甘肽八週後，所有受試者的黑色素指數顯著下降，而實驗結束後，他們也普遍感受到肌膚明顯變得更加亮白。
泰國一項隨機、雙盲、兩臂、安慰劑對照研究，研究口服穀胱甘肽對60名健康醫學生皮膚黑色素指數的影響。研究（研究連結）發現，在第四個星期，穀胱甘肽組中所有六個部位的黑色素指數持續下降，且對穀胱甘肽的耐受性良好。
一項雙盲隨機對照臨床試驗（研究連結），研究外用和口服穀胱甘肽作為皮膚美白劑，試驗持續 8 週。結果表明，接受外用和口服穀胱甘肽聯合療法的受試者，其黑色素指數（MI）和L評分顯著低於接受安慰劑的組別（P < 0.05）。研究指出，外用和口服穀胱甘肽均是有效的皮膚美白療法。
唯一獲得美國FDA-GRAS官方認證 口服穀胱甘肽有效提亮肌膚暗沉
研究顯示（研究連結），穀胱甘肽當作口服補充食品，可以幫助改善膚色不均，且它也獲得美國食品與藥物管理局（FDA）的GRAS（公認安全）認證。臨床研究也表明口服含有穀胱甘肽的保健品可幫助肌膚由內而外煥發光采，是一種有效又安全的煥亮肌膚方式。
穀胱甘肽能夠協助肌膚恢復自然、年輕的光彩。隨著身體內穀胱甘肽含量的自然減少，皮膚可能出現老化跡象，甚至呈現晦暗不均的狀態，而口服穀胱甘肽有助於對抗肌膚衰老問題，讓膚色重現勻亮光澤，並煥發青春活力。
口服穀胱甘肽能淡化表層、角質層，甚至深至真皮層的斑點
穀胱甘肽可以影響皮膚黑色素的生成，並阻斷導致黑色素過度增生的酵素。皮膚專科認證醫師Corey L.Hartman指出：「穀胱甘肽影響褐黑素的形成機制，使膚色更加均勻，並減少強烈紫外線暴露和環境污染所導致的自由基產生。」
文獻（研究連結）提及，穀胱甘肽的皮膚美白效果，是由酪胺酸酶的直接和間接的抑制，以及從真黑色素到褐黑色素產生的轉換所產生的。
穀胱甘肽能夠消除已存在於皮膚中的黑色素，包含各種存在於肌膚中的色素沉澱，對於表層、角質層、真皮層中的斑點都有淡化效果，有效消除深層黑斑，讓肌膚看起來更明亮淨白。
研究證實：連續食用8周穀胱甘肽，可減少85%細胞黑色素沈澱！
穀胱甘肽擁有全面的美白機制，可以抑制黑色素生成，同時降低紫外線對皮膚的傷害，還能協助維生素C促進生成膠原蛋白的效果加倍！
研究指出（研究連結），穀胱甘肽是極強的抗氧化劑，可以參與其他抗氧化劑如維生素C、E的作用，加強中和自由基功能，延緩皮膚細胞老化速度。專利研究指出，同時使用穀胱甘肽與維生素C能產生明顯加乘效果，使抗氧化效果提升23%，讓肌膚透亮有光澤、更細緻平滑。
另外，穀胱甘肽也可以抑制酪胺酸酶（Tyrosinase）的活性，阻礙黑色素的形成，研究（研究連結）指出連續食用10週的穀胱甘肽能有效抑制黑色素沈澱，使肌膚白皙透亮。
而根據目前唯一取得FDA GRAS認證及台灣TFDA許可的『天然型圓酵母穀胱甘肽OPITAC®』原廠證實（研究連結），連續食用穀胱甘肽8周，就可以減少85%細胞黑色素沈澱！
研究更表示穀胱甘肽可以促進膠原蛋白的分泌，還有助提升肌膚保水度、減少斑點粉刺、改善粗糙、增加平滑度好上妝、幫助防曬等多重好處，基本上食用4-8週就能感受肌膚變化。
護膚新概念「早P晚R」是什麼？事半功倍對抗衰老！
「早P晚R」其實是「早C晚A」的原型，原理來自2017年獲得年度諾貝爾生理學或醫學獎的晝夜節律理論，這一發現在保養領域被引入，證明了如果順應皮膚的作息來分配保養方式、就能事半功倍。
「早P晚R」核心理念在於修護與防護，將肌膚護理分為早晨（P，代表Protect）和晚上（R，代表Recover）兩個階段：
早P（Protect）是指在白天做好防護，特別是在肌膚受到陽光、污染物等外界環境損害的時候，需要進行包括抗藍光、抗污染、抗壓力、抗氧化等日間防護。此時選擇具有「抗氧化」效果且能增加肌膚防禦力的保養品，抗氧化成分能夠幫助中和自由基，減緩肌膚老化，同時提高肌膚的抵抗力。
晚R（Recover）則是指在夜間做好修護，當肌膚進入休息和修復的階段，需要以修護抗老為目標的晚間修護，以重建肌膚屏障、緩解敏感刺激。晚間應選擇含有「修護」成分的產品，幫助修復受損的細胞，舒緩肌膚的刺激，並減輕一天中所累積的壓力和損傷，有助於肌膚恢復健康光澤。
夜間護膚黃金期源於「肌膚生理機制」！代謝、修復、再生速度均最強
肌膚需要夜間護膚黃金期的主要原因在於：「夜晚是肌膚修護和再生的高度活躍時期」，夜晚具備特殊的生理機制和環境條件，使肌膚能夠更有效地進行自我修復和再生，讓肌膚保持健康、年輕和有彈性。
夜晚時，肌膚細胞的再生速度較白天快！因為在深夜，身體會釋放出生長激素，促進細胞修復和再生。且夜間的肌膚的代謝率提高，能更有效地吸收養分和修復受損的細胞。最重要的是，夜晚的細胞的DNA修復能力較強，可以修復受損的基因，減緩老化的過程。因此睡前充分攝取營養，可以讓肌膚在夜間加速細胞更新，更好地恢復透潤無瑕狀態！
夜間修復靠「穀胱甘肽」強效抗氧化！邊睡邊速效賦活肌底、抵禦自由基和活化細胞再生
我們的皮膚在白天不斷累積的壓力和損傷，如果不能在夜晚得到有效的修復，可能出現斷崖式老化！由於我們身體內部的生物鐘機制，肌膚的細胞修復機制在夜晚達到巔峰，所以睡眠時期是最重要的人體維修時間，也是真正的抗老關鍵！
「穀胱甘肽」具有強大的抗氧化能力，能夠捕獲、中和殘留的自由基，減少自由基對細胞分子的氧化損傷，能大幅減輕氧化帶來的損傷，抑制並擊退老化訊號，幫助肌膚細緻煥亮。同時，穀胱甘肽可以活化細胞再生，加速細胞修復和再生的過程，使細胞更快速地恢復功能與活力，以應對白天的損害。
晚上睡前口服補充穀胱甘肽，可以幫助身體速效進行細胞修復和再生，確保肌膚在夜間啟動深層快充修護力，持續賦活肌膚，以應對白天的損害，還能減少皮膚細胞的炎症，減輕紅腫和敏感症狀，起床即恢復原有的青春、膨潤與緊緻，同時完美鎖住肌齡。
「穀胱甘肽」流失危機：60歲人的穀胱甘肽水平會降至20%，低於70%以下易導致疾病
人體雖然能自行合成穀胱甘肽，但隨著年齡增長，體內合成穀胱甘肽的速度會越來越慢，且現代人經常外食且飲食不均，加上外在環境（如紫外線、空氣污染等）以及不良生活習慣（如抽菸、飲酒、熬夜和壓力等）等影響，會加速穀胱甘肽消耗與流失，而人體缺乏穀胱甘肽恐引發各種老化及相關疾病。
人體內穀胱甘肽含量會隨年齡增加而減少，60歲時體內穀胱甘肽水平可能降至20%以下，而當體內穀胱甘肽濃度低於70%以下時，容易導致疾病發生！
一旦流失速度大於合成速度，導致體內穀胱甘肽不足，將嚴重影響身體狀態，因此，適度補充穀胱甘肽以維持正常身體運作是關鍵！
什麼是「穀胱甘肽」？人體原生最強的抗氧化元素！
穀胱甘肽(Glutathione, GSH) 是由三種胺基酸(麩胺酸、胱胺酸和甘胺酸)組成的小分子蛋白質，是人體內含量最多的抗氧化劑，也是細胞的關鍵抗氧化物質，能與人體中的廢物結合，清除自由基。
穀胱甘肽是人體肝臟自行合成的一種重要物質，在人體內廣泛存在。它參與多種代謝過程，有助於清除身體內有害物質，同時能抑制自由基的生成，維持體內環境的平衡，保護身體免受氧化反應的影響，有助於維持生理機能。
然而，隨著年齡增長和外在環境因素的影響，體內穀胱甘肽逐漸減少，這可能導致身體容易受到氧化損害的風險增加。
人體60兆細胞都需穀胱甘肽！穀胱甘肽存在2種重要型態
穀胱甘肽（GSH）對於人體的大多數細胞都是必需的，在許多細胞的功能中發揮著重要作用，特別是對於身體的抗氧化防禦和解毒過程至關重要。穀胱甘肽作為一種強效的抗氧化劑，有助於保護細胞免受氧化損傷，並參與多種生理過程，如免疫系統功能、解毒、細胞信號傳遞等方面發揮關鍵作用。
穀胱甘肽（Glutathione）在人體中存在兩種主要形態：還原型態（GSH）和氧化型態（GSSG）。在正常情況下，人體內以還原型GSH為主，被認為是最具活性和有效的抗氧化劑。在人體內，穀胱甘肽還原酶（GR）的作用，使得穀胱甘肽能夠自由轉換這兩種型態，並發揮其抗氧化功能。
由於穀胱甘肽特殊的化學結構，穀胱甘肽在人體內有著重要的功能，不僅在肝臟中發揮解毒功能，還有助於保持肝臟健康，對於美白美容和抗衰老有相當的幫助。此外，穀胱甘肽協同維生素C、維生素E等其他抗氧化劑，可以增強其抗氧化能力，同時也有助於調節免疫系統的功能。
「穀胱甘肽」被譽為最強抗氧化物質、自由基收割機和人體最重要的解毒劑
穀胱甘肽是細胞內最強的抗氧化物質，被譽為「人體抗氧化之母」，在肝細胞內最多，濃度也相對其他組織更高，其次則是在腎臟細胞內。
穀胱甘肽，是人體本身存在的抗氧化劑，在抵禦氧化壓力方面發揮關鍵作用，可謂是貨真價實的「自由基收割機」，有助於減少自由基造成的細胞損傷，穩定並中和體內過多的自由基，維持細胞健康和整體生理平衡。
穀胱甘肽同時更是負責細胞的代謝與排毒的重要角色，特別在肝臟和腎臟的部位。穀胱甘肽在肝細胞中濃度最高，濃度與其他部位高出7-10倍，能將毒素溶於水，使其從尿液中排出體外，促進我們代謝體內所累積的懸浮微粒、過量重金屬、環境汙染物等有毒物，因此也是人體最重要的解毒劑。
細胞內最強的抗氧化物質「穀胱甘肽」是抗衰老關鍵！
當人體攝取食物後，營養物質如葡萄糖、脂質和蛋白質經過消化分解，進入細胞後通過粒線體的糖解作用、檸檬酸循環和呼吸作用等方式，產生能量供應身體所需。這些能量產生的過程涉及電子轉移，這可能會產生自由基，進而導致氧化壓力。
氧化壓力與老化有密切關係。科學研究已證實，氧化壓力可能造成細胞損傷和死亡，是導致細胞老化和衰退的關鍵因素。老化細胞在多個方面與健康細胞不同，例如氧化蛋白損傷增加、細胞核膨脹以及粒線體受損等。
研究也指出，抗氧化劑對控制細胞老化具有一定的積極作用。而人體中最強的抗氧化劑正是穀胱甘肽，是數量最多而且最重要的水溶性抗氧化劑，能夠對抗與年齡相關的發炎和氧化壓力，能幫助消除體內所產生的自由基，穩定細胞氧化的狀態。
穀胱甘肽5大功效
穀胱甘肽是人體內強效的抗氧化劑，能幫助清除自由基、調節各式身體機能，以下整理了穀胱甘肽主要5大功效：
穀胱甘肽功效1 :啟動肌膚美白力、促進膠原蛋白合成同時抗皺、抵禦外在老化因子
穀胱甘肽美白效果顯著！這是因為穀胱甘肽能夠幫助肌膚抵禦紫外線輻射的傷害，透過抑制酪氨酸酶的活性，減少黑色素細胞的合成，使肌膚變得更淨白透亮，減少色斑和黑色素沉著，從而改善膚色不均和暗沉的問題。
同時，穀胱甘肽具有強大的抗氧化性能，有助於提升肌膚細胞的活力，減少自由基對細胞的損害，還被證實可以促進一型膠原蛋白的生成，能夠高效對抗皺紋與鬆弛問題，大幅增加肌膚彈性和潤澤度，因此能讓肌膚擁有透亮緊緻的光澤，重現柔嫩絲滑的年輕澎潤觸感。
另外，人類外表的變化與體內過多的危險因子密切相關。這些危險因子可能會對支撐和維持肌膚光滑彈力的物質，如膠原蛋白和彈性纖維造成損害。同時，它們也參與了黑色素的生成，使得外觀看起來比實際年齡更為老化。
研究表明，穀胱甘肽具有強大的能力，能夠有效地消除這些危險因子，同時調節抗氧化營養素，例如維生素C和E。這有助於增加肌膚的平滑度和光亮程度，對養顏美容和保持年輕有著積極的作用。
此外，穀胱甘肽也被發現對助眠和保持良好氣色有所幫助。研究指出，穀胱甘肽能夠抑制腦部中的興奮性神經傳導物質，從而有助於安定精神，進而產生舒眠的效果。含有高量穀胱甘肽的人不僅入睡更快，而且醒來後感覺更加清爽，有助於保持良好的氣色。
穀胱甘肽功效2:強效抗氧化與抗老化、調理生理機能與促進代謝
穀胱甘肽作為超強效抗氧化劑，是人體抗氧化系統的關鍵樞紐，有助於對抗老化。它具有清除自由基的能力，進而能有效減少自由基對身體造成的損害，提升肌膚的保護能力，並降低黑色素的生成，有助於調整體質，還能延緩細胞老化速度。
穀胱甘肽也能幫助體內其他抗氧化劑作用，如維生素C、E、硫辛酸及多酚類物質（如兒茶素、白藜蘆醇）也需要足夠的穀胱甘肽來發揮效果，才能中和自由基，對於調節生理機能極為重要。因此，補充穀胱甘肽時若搭配維生素C、天然多酚等營養素，有助於提升整體抗氧化效果。
此外，危險因子對身體的影響不僅限於外表，同時可能導致生理機能失調和代謝問題，長期下來對整體健康造成危害。穀胱甘肽有助於減少這些危險因子的數量，減輕身體的壓力，維持正常的生理機能，促進新陳代謝，有助於保持身體的健康狀態。
研究顯示：老年人補充高劑量「合成穀胱甘肽關鍵胺基酸」，能改善身體發炎、腰部脂肪和抗老化，且具備高安全性
一項研究（研究連結）旨在探討在老年人身上補充甘氨酸和N-乙醯半胱氨酸（GlyNAC）對改善穀胱甘肽缺乏、氧化壓力、粒線體功能障礙、發炎、身體功能和老化標誌的影響。
研究對老年人進行為期16週的GlyNAC高劑量補充，分別為：甘氨酸和N-乙醯半胱氨酸各100毫克/公斤/天，丙氨酸為200毫克/公斤/天。以上三種物質是穀胱甘肽合成所需的關鍵胺基酸，可以促進體內穀胱甘肽的合成，提高穀胱甘肽的水平。
結果顯示，補充GlyNAC能夠改善老年人身上所觀察到的老化問題，包括提高穀胱甘肽濃度、降低氧化壓力、改善粒線體功能、減少發炎、改善內皮功能、減輕胰島素抗性、減緩多種老化特徵、改善身體功能、減少腰圍、降低收縮壓等。
研究結論指出，在老年人身上補充GlyNAC為期16週，是安全且耐受性良好的，能夠抗氧化、改善並逆轉與年齡相關的多種異常與老化問題，有助於促進老年人的健康狀態。
穀胱甘肽功效3:保肝排毒、強效代謝與解除宿醉
日常生活中接觸的各種毒素，都需要肝細胞進行解毒，而這個過程需要大量的穀胱甘肽來中和毒性物質，清除自由基，並協助肝細胞進行代謝，以避免毒素和自由基對肝臟細胞造成損傷。穀胱甘肽能將毒素溶解於水中，促使其從尿液中排出體外。因此，在許多護肝產品中常添加穀胱甘肽，發揮護肝保肝作用。
穀胱甘肽能預防酒精性脂肪肝、改善非酒精性脂肪肝。一項由日本OPITAC®穀胱甘肽原廠的實驗證實，口服穀胱甘肽(GSH)能降低飲酒後肝臟中的總脂肪、三酸甘油酯的增加幅度，對於預防酒精性脂肪肝有顯著功效。另一項探討口服穀胱甘肽對非酒精性脂肪肝的治療作用，發現ALT(肝功能指數，即GPT)、三酸甘油脂也有顯著降低。
此外，穀胱甘肽還能有效解除宿醉。一項針對100位男性的實驗發現，相較於給予安慰劑的對照組，服用穀胱甘肽的組別在飲酒後血液中的酒精濃度和乙醛濃度明顯降低。同時，穀胱甘肽組在酒精呼氣測試中濃度降低了50%，並且對於宿醉症狀，如頭痛和噁心等有顯著改善。
穀胱甘肽功效4:幫助入眠、打造高品質深層好睡眠、減輕疲勞感
臨床實驗指出，壓力引起的自由基在人體內會導致腦細胞長期發炎，進而影響睡眠品質。而穀胱甘肽具有抑制腦中興奮性神經傳遞物質麩胺酸的作用，有助於安定神經，進而產生舒眠的效果。
近期研究發現，穀胱甘肽含量高的人不僅入睡更快、睡眠品質更好，而且醒來後感覺更加清爽。
補充適量的穀胱甘肽，還有助於改善腦細胞的氧化狀況，減輕疲勞感，同時有助於腎上腺皮質醇的調節，從而達到放鬆的效果。根據日本的研究，受試者在睡前30至60分鐘使用穀胱甘肽，可以顯著增加總睡眠時間和非快速動眼期的睡眠品質。
另外，穀胱甘肽也能使粒線體作用提升，減少乳酸堆積，讓使用者可以更快速的提升活力、減少疲勞感。
穀胱甘肽功效5:提升免疫力，強化身體防禦保護力
人體內的危險因子會因年齡增長、不良的生活飲食習慣等因素而增加。這些危險因子可能攻擊身體的各個部位，威脅身體的防禦力。穀胱甘肽就像是身體的守護者，巡視全身，發現危險因子後會採取行動，將其抓住並排除，以保護身體免受危險因子的傷害，增強身體的保護能力。
自由基在人體免疫防禦中扮演重要角色。正常情況下，人體內應該有一定量的自由基來預防疾病，但過多的自由基會導致細胞氧化損傷。維持這種平衡的關鍵在於抗氧化系統的中心——穀胱甘肽。如果身體缺乏穀胱甘肽，容易受到細菌和病毒感染，進而引發疾病。
許多疾病，如愛滋病（HIV病毒感染）、流感病毒感染、流感合併肺炎鏈球菌感染、肺部囊性纖維化（假單胞菌感染）等患者，其體內穀胱甘肽水平通常低於一般人。另外一種罕見的遺傳性疾病—穀胱甘肽合成酶缺乏症（oxoprolinuria），患者常表現為反覆的細菌感染。
因此，若人體內含有足夠的穀胱甘肽，能幫助淋巴細胞增殖，提高免疫力，減少有害物質侵入，進而降低罹患癌症的風險。
哪些人適合吃穀胱甘肽？
適合補充榖胱甘肽的族群主要包括：
- 年長者因身體老化易缺乏穀胱甘肽
- 經常外食、飲食攝取不均者
- 想要美白抗老者
- 睡眠品質不佳者
- 想促進身體代謝者
- 免疫力較低、經常感冒者
- 抽菸、喝酒族
- 曝露於空汙、紫外線者
- 經常疲憊、缺乏活力者
穀胱甘肽何時吃最有效？
穀胱甘肽在任何時候吃都可以，可以根據自己的目的與用途來決定攝取時間：
1.飯後吃
如果妳是透過口服穀胱甘肽補充劑來補充體內穀胱甘肽，建議在用餐後攝取。由於飯後的血糖水平會升高，促進胰島素的釋放，而胰島素有助於促進穀胱甘肽的吸收。
2.睡前吃、晚上吃
如果妳希望穀胱甘肽有助於提升睡眠品質或幫助更好地入睡，可選擇在晚餐後或睡前一小時服用。
穀胱甘肽有副作用嗎？
穀胱甘肽是一種安全的食品，在食用適量穀胱甘肽的前提下，一般不會有副作用產生，目前也尚未有研究指出關於穀胱甘肽的任何副作用問題。
不過，極少部分的人在「過量」攝取後，可能會出現消化道不適、噁心、想吐、腹瀉或皮膚紅腫、搔癢等。
穀胱甘肽多存於哪些食物中？
榖胱甘肽廣泛存在於各種食物當中，其中以新鮮未加工蔬果及肉類含量較多。以下是一些有助於提高穀胱甘肽水平的食物：
- 富含穀胱甘肽的食物：蘆筍、酪梨、菠菜、秋葵、四季豆、小黃瓜、木瓜、番茄、芒果、櫛瓜、辣椒、草莓等。
- 含有穀胱甘肽合成所需原料的食物：十字花科蔬菜，如：花椰菜、高麗菜、芝麻葉、白蘿蔔、羽衣甘藍、捲心菜，蒜頭、韭菜、洋蔥、扁豆、豌豆、堅果、肉類等。
- 富含硒的食物：海鮮及肉類，是協助GSH抗氧化的重要營養素。
- 含維生素C和Ｅ的食物：新鮮水果（芭樂、柑橘類、奇異果）及深綠色蔬菜，維生素C和E皆是協助榖胱甘肽抗氧化功能的重要幫手，可以增加血液中的GSH含量。
- 富含維生素B6及B12的食物：維生素B6及B12做為榖胱甘肽的輔助營養素，適量攝取魚類（鮭魚、秋刀魚）、紅肉、乳製品及蛋類也對健康有益。
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